The Bioinformatics Core at Memorial Sloan Kettering Cancer Center provides a wide range of computational services to support researchers with varying expertise in computing. Our services include standard bioinformatics pipelines such as variant calling, RNA-Seq, and single-cell RNA-Seq, along with custom analysis workflows for novel data types. We specialize in advanced areas like spatial proteomics, AI-driven analysis, and developing tools like web apps and databases. Additionally, we offer data management, high-quality graphic generation for publications, and comprehensive support for grant writing. The core also provides training and consulting in computational methods and stays updated with the latest Bioinformatics advancements.